I have one copy of each gene, and it has contributed to a huge list of medical problems for me, once the Millennium Falcon lone star falcon made the trip across Texas parsecs shirt genes were activated. Adam Jones yes, with just one copy, there can be less effective. But when you have two copies, one of each, like I do your ability to detox and just clear daily metabolic wastes is 70-90% impaired. My chemotherapy became extremely toxic very early on and I had to discontinue it after 6 of 8 scheduled treatments. Some people even have three copies of the gene, as well as other co-mutations. Fenn, I’ve read up on some of this after having issues with vitamin b12 deficiency as part of the diagnosis for other health problems.